With multiple delivery methods in development, Starton can expand the number of medicines it is able to deliver continuously, based on patients’ individualized needs and provide multiple avenues for success.

Product Active Indication Preclinical Phase 1 Phase 1b Phase 2 Phase 3
STAR-LLD-SCsubcutaneous infusion
Lenalidomide
Standard Risk Relapsed Refractory Multiple Myeloma (RRMM)
STAR-LLD-OCRoral controlled release
Lenalidomide
Chronic lymphocytic leukemia (CLL)
STAR-LLD-OCRoral controlled release
Lenalidomide
High Risk Relapsed Refractory Multiple Myeloma (RRMM)
STAR-LLD-SCsubcutaneous infusion
Lenalidomide
Combination with CAR T cell therapies

STAR-LLD broadly refers to our lead candidate, a controlled delivery of low-dose lenalidomide which enables better tolerability, thus longer drug exposure at effective doses which may potentially improve PFS, OS, as well as quality of life.

STAR-LLD-SC is currently in Phase 2 testing for the treatment of relapsed/refractory multiple myeloma RRMM and represents the first clinical demonstration of Temporal Controlled Pharmacology. STAR-LLD is also being studied in Investigator Initiated Trials in in combination with both bispecifics and CAR-T cell therapies, in multiple myeloma and lymphoma.

Other active ingredients are being researched at our facility that have not yet been disclosed.

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